Network Pharmacological Analysis of Hydroxychloroquine Intervention in the Treatment of Iga Nephropathy

This study proved that hydroxychloroquine may treat IgAN through the TLR signaling pathway, and the restraint of TNF, TLR, IL1B, and JUN may be essential for the treatment.

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Publication Details

Journal
Current Pharmaceutical Design
Published
2024-11-04
DOI
https://doi.org/10.2174/0113816128347345241028063515
Citations
1
Primary Topic
Renin-Angiotensin System Studies
Type
article
Field-Weighted Citation Impact
0.40

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article

Network Pharmacological Analysis of Hydroxychloroquine Intervention in the Treatment of Iga Nephropathy

Shuwang Ge, Kanglin Guo, Gang Xu, Yichun Cheng et al.
1 citations
Current Pharmaceutical Design
Renin-Angiotensin System Studies
0.40
article

Network Pharmacological Analysis of Hydroxychloroquine Intervention in the Treatment of Iga Nephropathy

Shuwang Ge, Kanglin Guo, Gang Xu, Yichun Cheng, Mengxiao Zou, Qian Duo
article en
1 citations

Abstract

This study proved that hydroxychloroquine may treat IgAN through the TLR signaling pathway, and the restraint of TNF, TLR, IL1B, and JUN may be essential for the treatment.

Current Pharmaceutical DesignVol. 31(9)
Tongji Hospital (CN), Huazhong University of Science and Technology (CN)
National Natural Science Foundation of China, Natural Science Foundation of Hubei Province, National Key Research and Development Program of China
Good health and well-being
Openalex Percentile: Top 31%
Renin-Angiotensin System Studies
0.40
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