Enhanced Neuroprotection in Experiment Multiple Sclerosis through Combined Rosiglitazone and Probiotic-loaded Solid Lipid Nanoparticles: Modulation of Cellular Signaling Pathways
The study showed that combining RSG and probiotics in an experimental medication form improved symptoms of MS more effectively than using RSG alone. This improvement is likely due to changes in STAT-3, mTOR, and PPAR-gamma signaling pathways.
Authors
- Alok Pratap Singh (ORCID: https://orcid.org/0000-0002-6387-0930)
- Sidharth Mehan (ORCID: https://orcid.org/0000-0003-0034-835X)
- Nitish Kumar
- Nidhi Tyagi (ORCID: https://orcid.org/0000-0002-8631-2990)
Institutions
- SRM Institute of Science and Technology (IN)
- Indo Soviet Friendship College of Pharmacy (IN)
Publication Details
- Journal
- CNS & Neurological Disorders - Drug Targets
- Published
- 2024-11-04
- DOI
- https://doi.org/10.2174/0118715273336107241015100912
- Citations
- 3
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 0.72