Cancer immunogenic cell death via pyroptosis with CXCR4-targeted nanotoxins in hepatocellular carcinoma
Our findings demonstrate the activation of the innate immune response in HCC by inducing pyroptosis with T22-PE24 nanotoxin treatment and support an implementation of this strategy for HCC treatment.
Authors
- Yihu Li (ORCID: https://orcid.org/0000-0001-7049-8631)
- Rui He (ORCID: https://orcid.org/0000-0002-8314-9155)
- Xingyuan Jiao (ORCID: https://orcid.org/0000-0003-3113-934X)
- Zheng Zhao (ORCID: https://orcid.org/0000-0002-9898-0232)
- Yingbin Huang (ORCID: https://orcid.org/0009-0000-6617-7050)
- Shuyi Dong
Institutions
- Sun Yat-sen University (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Sun Yat-sen University Cancer Center (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2024-11-04
- DOI
- https://doi.org/10.3389/fbioe.2024.1433126
- Citations
- 5
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 1.20