Silylation of Nitrogen-Containing Compounds Using Trimethylsilylimidazole in the Active Medium of Hexamethyldisilazane

A new silylating system is suggested based on trimethylsilylimidazole in the active medium of hexamethyldisilazane, which allows for the introduction of trimethylsilyl units both at the OH and NH2 groups. The use of this system ensures the synthesis of trimethylsilyl derivatives of amino alcohols in one stage, and, in the case of aniline and N,N-dimethylhydrazine, significantly reduces the reaction time and increases the product yields.