Novel Adiposity Indices Are Associated With Poor Prognosis in Heart Failure With Preserved Ejection Fraction Without the Obesity Paradox
An elevated BMI over a certain range was associated with a reduced risk of all-cause death in heart failure with preserved ejection fraction, displaying a U-shaped relationship, with no mortality reduction observed in cases of extreme obesity. In contrast, higher values of novel obesity indices were positively correlated with all-cause death and heart failure hospitalization without the obesity paradox.
Authors
- Huixia Lu (ORCID: https://orcid.org/0000-0003-0131-5808)
- Cheng Zhang (ORCID: https://orcid.org/0000-0003-3672-6543)
- Panpan Xu (ORCID: https://orcid.org/0009-0009-2064-7200)
- Changjiang Wei
- Tianhao Wei
- Shuai Zhang (ORCID: https://orcid.org/0009-0001-7504-023X)
- Yanling Zhang (ORCID: https://orcid.org/0000-0001-6381-1765)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2024-11-04
- DOI
- https://doi.org/10.1161/jaha.124.035430
- Citations
- 7
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 2.81
Funders
- National Key Research and Development Program of China
- National Heart, Lung, and Blood Institute