Bleeding Associated With Antiarrhythmic Drugs in Patients With Atrial Fibrillation Using Direct Oral Anticoagulants: A Nationwide Population Cohort Study
Concomitant use of DOACs with amiodarone, but not dronedarone or propafenone, increases the risk of major bleeding, particularly intracranial bleeding. This study provides new evidence to guide clinicians to tailor concomitant anticoagulation and antiarrhythmic therapy for patients with atrial fibrillation.
Authors
- Yu‐Tung Huang (ORCID: https://orcid.org/0000-0003-3224-7238)
- Hui‐Tzu Tu
- Chun‐Li Wang
- Victor Chien‐Chia Wu (ORCID: https://orcid.org/0000-0002-9918-4369)
- Kuo‐Chun Hung (ORCID: https://orcid.org/0000-0001-8655-3711)
- Chang‐Fu Kuo (ORCID: https://orcid.org/0000-0002-9770-5730)
- Shang‐Hung Chang (ORCID: https://orcid.org/0000-0003-0462-2344)
- Shao‐Wei Chen (ORCID: https://orcid.org/0000-0003-1674-1295)
- Ming‐Shien Wen (ORCID: https://orcid.org/0000-0002-0056-7985)
- Yu‐Chang Huang (ORCID: https://orcid.org/0009-0007-6718-750X)
Institutions
- Chang Gung University of Science and Technology (TW)
- University of Nottingham (GB)
- National Health Research Institutes (TW)
- Chang Gung University (TW)
- Chang Gung Memorial Hospital (TW)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2024-11-04
- DOI
- https://doi.org/10.1161/jaha.123.033513
- Citations
- 6
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 2.41
Funders
- Sanofi
- Chang Gung Medical Foundation
- Center for Big Data Analytics and Statistics, Chang Gung Memorial Hospital
- Center for Big Data Analytics, University of Texas at Austin