Integrated Genetic and Cellular Analysis Reveals NLRP1 Activation in CD4+ T Lymphocytes During Chronic HIV Infection
PLWH CD4+ T cells are more prone to IL-1β release and pyroptosis, therefore contributing to chronic inflammation.
Authors
- Edione C. Reis
- Alessandra Pontillo (ORCID: https://orcid.org/0000-0002-7883-0640)
- Mariela Estefany Gislene Vera Roa (ORCID: https://orcid.org/0000-0003-2418-8477)
- Vinícius Nunes Cordeiro Leal (ORCID: https://orcid.org/0000-0001-6049-6907)
- Amanda Nazareth Lara (ORCID: https://orcid.org/0000-0002-4294-0282)
- Julia Silva Cantoni
Institutions
- Universidade de São Paulo (BR)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
Publication Details
- Journal
- Immunological Investigations
- Published
- 2024-11-04
- DOI
- https://doi.org/10.1080/08820139.2024.2419940
- Citations
- 3
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico