Identifying causal relationships between 35 blood and urine biomarkers and urologic cancers: MR-meta combined with Bayesian colocalization Mendelian randomization analysis
This study identified significant biomarkers associated with urological cancers in blood and urine. These include GGT, IGF 1, and Lp(a), which are strong biomarkers for PCa. In addition, the findings of this study provide evidence for a handful of risk and protective factors for the development of urologic cancers.
Authors
- Chengyi Zhao
- Yinghui Zhang (ORCID: https://orcid.org/0000-0002-4588-7819)
- Zhi Qiao (ORCID: https://orcid.org/0000-0002-2158-4901)
- Wenxin An
- Yaru Wang (ORCID: https://orcid.org/0000-0002-6789-071X)
Institutions
- Harbin Medical University (CN)
- Third Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2024-11-04
- DOI
- https://doi.org/10.1007/s12672-024-01493-0
- Citations
- 2
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.10
Funders
- Harbin Medical University