Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial
Intestinal subtype is a histologic biomarker of enhanced sensitivity of gastric adenocarcinoma to NAIC. The intestinal subtype-specific signature model is applicable to guide NAIC for patients with locally advanced gastric adenocarcinoma.
Authors
- Xiu‐Wu Bian (ORCID: https://orcid.org/0000-0003-4383-0197)
- Linghong Wan (ORCID: https://orcid.org/0009-0002-4282-0421)
- Qi‐Yue Chen (ORCID: https://orcid.org/0000-0001-6391-4043)
- Xianfeng Li (ORCID: https://orcid.org/0000-0002-8024-7980)
- Yongying Hou
- Qihua Zhang
- Yuanfeng Ren
- Mengsi Zhang
- Shunan Wang (ORCID: https://orcid.org/0000-0001-8658-6441)
- Shuoran Tian
- Mengxia Li (ORCID: https://orcid.org/0000-0003-4443-740X)
- Ze-Ning Huang (ORCID: https://orcid.org/0000-0001-7284-3689)
- Zhong‐yi Qin (ORCID: https://orcid.org/0000-0002-5504-9480)
- Fan Li (ORCID: https://orcid.org/0000-0002-5604-530X)
- Jinyang Li (ORCID: https://orcid.org/0009-0000-6057-8937)
- Tao Wang (ORCID: https://orcid.org/0000-0003-4442-8829)
- Bin Wang (ORCID: https://orcid.org/0000-0001-5574-1760)
- Hui Luo (ORCID: https://orcid.org/0000-0001-6312-9299)
- Dongfeng Chen (ORCID: https://orcid.org/0000-0003-1700-2195)
- Xiao Hu
- Mengyi Han (ORCID: https://orcid.org/0009-0008-8642-6809)
- Shiyin Peng (ORCID: https://orcid.org/0000-0002-6484-0805)
- Yuting Tan
- Mengting Sun (ORCID: https://orcid.org/0000-0002-8517-8451)
- Jianwu Zhu
- Junyv Xiang
- Lei Wang (ORCID: https://orcid.org/0009-0009-8121-7036)
- Qin Liu (ORCID: https://orcid.org/0000-0003-3760-6930)
- Ziyi Peng
- Yuwei Pan
- Lijing Wu (ORCID: https://orcid.org/0000-0002-0736-9826)
Institutions
- Fujian Medical University (CN)
- Army Medical University (CN)
- Sun Yat-sen University (CN)
- Chongqing University (CN)
- Daping Hospital (CN)
- Nanfang Hospital (CN)
- Southwest Hospital (CN)
- Sun Yat-sen University Cancer Center (CN)
- Jiangjin Central Hospital (CN)
- Union Hospital (CN)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2024-11-04
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-2436
- Citations
- 8
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 3.35
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Chongqing
- Army Medical University
- National Key Research and Development Program of China
- Chongqing Graduate Student Research Innovation Project