Modeling Transport of Ca2+ in Neural Synapse with Boltzmann Equation and Electrodynamics

The transport of ions such as Calcium 2+ plays a relevant role in neural synapse. Because the electric charge of neurotransmitters, Boltzmann equation as well as well-known equations of classical electrodynamics can be used to explore electrical properties of synapse. In order to accomplish this, an axes of symmetry so that the geometry of axon as a cylinder, was assumed. In essence, equation models the entry of intracellular Calcium 2+ known as voltage-gated N-type calcium channels into neurons. Inside axon ions produce waves that are responsible to produce electric interactions with synaptic vesicles as well as neurotransmitters. Thus it is expected a well-defined electrodynamics that allows to neurotransmitters to pass along cleft towards postsynaptic neuron. In this manner, current and voltage by using the Boltzmann equation have been derived. It is shown that both the Calcium 2+ ions trigger a well-defined electrodynamics for neurotransmitters.

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Published
2024-09-18
DOI
https://doi.org/10.1109/argencon62399.2024.10735717
Primary Topic
Neural dynamics and brain function
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article
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Modeling Transport of Ca2+ in Neural Synapse with Boltzmann Equation and Electrodynamics

Huber Nieto–Chaupis
Neural dynamics and brain function
article

Modeling Transport of Ca2+ in Neural Synapse with Boltzmann Equation and Electrodynamics

Huber Nieto–Chaupis
article en

Abstract

The transport of ions such as Calcium 2+ plays a relevant role in neural synapse. Because the electric charge of neurotransmitters, Boltzmann equation as well as well-known equations of classical electrodynamics can be used to explore electrical properties of synapse. In order to accomplish this, an axes of symmetry so that the geometry of axon as a cylinder, was assumed. In essence, equation models the entry of intracellular Calcium 2+ known as voltage-gated N-type calcium channels into neurons. Inside axon ions produce waves that are responsible to produce electric interactions with synaptic vesicles as well as neurotransmitters. Thus it is expected a well-defined electrodynamics that allows to neurotransmitters to pass along cleft towards postsynaptic neuron. In this manner, current and voltage by using the Boltzmann equation have been derived. It is shown that both the Calcium 2+ ions trigger a well-defined electrodynamics for neurotransmitters.

Universidad Autónoma del Perú, National University of Engineering (PE)
Openalex Percentile: Top 80%
Neural dynamics and brain function
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Modeling Transport of Ca2+ in Neural Synapse with Boltzmann Equation and Electrodynamics — Huber Nieto–Chaupis · (2024) | TGRS Research Map | TGRS