Association of the humoral immune response with the inflammatory profile in Plasmodium vivax infections in pregnant women
An association between the humoral immune response and the peripheral inflammatory cytokine profile with the adverse outcomes in malaria in pregnancy by P. vivax was observed. Previous exposure to the parasite can influence the IL-6 and IL-10 response, which is associated with increased parasitemia, reduced maternal weight gain and premature delivery.
Authors
- Erika Paula Machado Separovic
- Cláudio Romero Farias Marinho (ORCID: https://orcid.org/0000-0002-1227-3845)
- Susana Campino (ORCID: https://orcid.org/0000-0003-1403-6138)
- Sabrina Epiphânio (ORCID: https://orcid.org/0000-0001-6094-9750)
- Laura Cordeiro Gomes (ORCID: https://orcid.org/0000-0002-7161-0098)
- Jamille Gregório Dombrowski (ORCID: https://orcid.org/0000-0002-1863-1914)
- Gerhard Wunderlich (ORCID: https://orcid.org/0000-0003-1724-0337)
- Rodrigo Medeiros de Souza (ORCID: https://orcid.org/0000-0002-7775-6901)
- Taane Gregory Clark (ORCID: https://orcid.org/0000-0001-8985-9265)
- Oscar Murillo (ORCID: https://orcid.org/0000-0003-1204-7984)
- Bruna Beatriz Pedroza de Melo
- Maria Inês dos Santos (ORCID: https://orcid.org/0000-0001-5826-6782)
Institutions
- Universidade Federal do Acre (BR)
- Universidade de São Paulo (BR)
- London School of Hygiene & Tropical Medicine (GB)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2024-11-04
- DOI
- https://doi.org/10.1371/journal.pntd.0012636
- Citations
- 1
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.24
Funders
- UK Research and Innovation
- Universidade Federal do Acre
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Medical Research Council