SARS-CoV-2 disrupts host gene networks: Unveiling key hub genes as potential therapeutic targets for COVID-19 management
By elucidating the genetic mechanisms induced by the virus, the current research provides significant information that can be employed to create new targeted therapeutic strategies for future research and treatment related to COVID-19. Moreover, the findings highlight potentially promising therapeutic biomarkers for early risk assessment of critically ill patients.
Authors
- Jakub Sawicki (ORCID: https://orcid.org/0000-0002-4759-8113)
- Ewa Lepiarczyk (ORCID: https://orcid.org/0000-0003-2998-9468)
- Leszek Gromadziński (ORCID: https://orcid.org/0000-0002-8827-4203)
- Piotr Kocbach (ORCID: https://orcid.org/0000-0001-5149-6702)
- Łukasz Paukszto (ORCID: https://orcid.org/0000-0002-3618-1064)
- Marta Wiszpolska (ORCID: https://orcid.org/0000-0002-9334-8975)
- Beata Moczulska (ORCID: https://orcid.org/0000-0002-8852-4137)
- Marta Majewska (ORCID: https://orcid.org/0000-0001-5856-6929)
- Anna Górska (ORCID: https://orcid.org/0000-0003-3305-8711)
- Karol G. Makowczenko (ORCID: https://orcid.org/0000-0003-3758-4452)
- Aleksandra Lipka (ORCID: https://orcid.org/0000-0003-0815-6635)
- Katarzyna Krawczyk (ORCID: https://orcid.org/0000-0001-9019-0490)
- Mateusz Maździarz (ORCID: https://orcid.org/0000-0002-7278-4604)
Institutions
- University of Oslo (NO)
- University of Computer Sciences and Economics in Olsztyn (PL)
- InLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences (PL)
- University of Warmia and Mazury in Olsztyn (PL)
Publication Details
- Journal
- Computers in Biology and Medicine
- Published
- 2024-11-04
- DOI
- https://doi.org/10.1016/j.compbiomed.2024.109343
- Citations
- 4
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 1.56