Integration of transcriptomics and metabolomics to study the mechanism of Siwei Huangqi powder in Tibetan medicine for protecting against high-altitude hypoxic brain injuries
The therapeutic effect of SWHQP on brain injury in HHBI rats is attributed to its ability to regulate inflammation-related amino acid synthesis and lipid metabolism and modulate inflammation-related pathways. These findings provide a robust research foundation for the potential clinical application of SWHQP in Tibetan medicine.
Authors
- Na Zhang (ORCID: https://orcid.org/0009-0005-2591-599X)
- X R Zhang (ORCID: https://orcid.org/0000-0003-1079-7132)
- Wangjie Cao (ORCID: https://orcid.org/0000-0001-6412-8941)
- Congyi Li
- Jianzheng He
- Yongqi Liu (ORCID: https://orcid.org/0000-0001-8327-432X)
- Hongxia Gong
- Yong Qing Huang (ORCID: https://orcid.org/0000-0002-1158-5601)
- Jiawang Guo
Institutions
- Gansu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Traditional and Complementary Medicine
- Published
- 2024-11-04
- DOI
- https://doi.org/10.1016/j.jtcme.2024.11.002
- Primary Topic
- High Altitude and Hypoxia
- Type
- article
- Field-Weighted Citation Impact
- 0.00