Tetrahydrocurcumin targets TRIP13 inhibiting the interaction of TRIP13/USP7/c-FLIP to mediate c-FLIP ubiquitination in triple-negative breast cancer
These findings offer new insights into the novel molecular mechanisms of anti-TNBC effects of THC and present a promising targeted therapeutic strategy for TNBC.
Authors
- Qiuju Zhang (ORCID: https://orcid.org/0000-0003-3407-2136)
- X. Sun (ORCID: https://orcid.org/0000-0003-4409-4574)
- Jichao Zhang (ORCID: https://orcid.org/0000-0002-7400-6726)
- Kang Ning (ORCID: https://orcid.org/0000-0003-3325-5387)
- Zebin Shang
- Qiang Zhang (ORCID: https://orcid.org/0000-0002-8862-3098)
- Chengxiao Zhao (ORCID: https://orcid.org/0000-0002-6373-8710)
- Shijie Cao (ORCID: https://orcid.org/0000-0001-9164-882X)
- Zhiyong Cao
- Feng Qiu
- Yujie Sun (ORCID: https://orcid.org/0000-0003-4751-639X)
- Xiumei Gao
- Bing-Yang Zhang
Institutions
- Tianjin University of Traditional Chinese Medicine (CN)
- Tianjin Medical University Cancer Institute and Hospital (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2024-11-04
- DOI
- https://doi.org/10.1016/j.jare.2024.11.004
- Citations
- 13
- Primary Topic
- Ubiquitin and proteasome pathways
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- National Natural Science Foundation of China
- Zhejiang University