Metastatic Neuroblastoma Mimicking Multiple Infantile Hemangiomas Diagnosed With Ultrasound

Neuroblastoma is a malignant tumor derived from the neural crest cells that often involves the adrenal glands and rarely metastasizes to the skin. Here, we present a case of a nine-month-old male infant who presented with multiple noncompressible blue-purple subcutaneous nodules, initially suggestive of atypical deep hemangiomas. The ultrasound revealed a lack of increased vascularity of the masses and an adrenal mass, leading to a biopsy and diagnosis of a neuroblastoma involving the adrenal gland, liver, and skin. We demonstrate that metastatic neuroblastoma can mimic infantile hemangiomas and that noncompressible skin masses warrant further workup with ultrasonography to rule out neuroblastoma.

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Publication Details

Journal
Cureus
Published
2024-11-04
DOI
https://doi.org/10.7759/cureus.73013
Primary Topic
Neuroblastoma Research and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Metastatic Neuroblastoma Mimicking Multiple Infantile Hemangiomas Diagnosed With Ultrasound

Monique G. Kumar, Ashley N Houff, Sharon E Albers
Cureus
Neuroblastoma Research and Treatments
article

Metastatic Neuroblastoma Mimicking Multiple Infantile Hemangiomas Diagnosed With Ultrasound

Monique G. Kumar, Ashley N Houff, Sharon E Albers
article en

Abstract

Neuroblastoma is a malignant tumor derived from the neural crest cells that often involves the adrenal glands and rarely metastasizes to the skin. Here, we present a case of a nine-month-old male infant who presented with multiple noncompressible blue-purple subcutaneous nodules, initially suggestive of atypical deep hemangiomas. The ultrasound revealed a lack of increased vascularity of the masses and an adrenal mass, leading to a biopsy and diagnosis of a neuroblastoma involving the adrenal gland, liver, and skin. We demonstrate that metastatic neuroblastoma can mimic infantile hemangiomas and that noncompressible skin masses warrant further workup with ultrasonography to rule out neuroblastoma.

CureusVol. 16(11)
University of Central Florida (US), University of South Florida (US), AdventHealth Orlando (US), AdventHealth East Orlando (US)
Openalex Percentile: Top 69%
Neuroblastoma Research and Treatments
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