Noncanonical microglial IL-1β maturation in chronic kidney disease
These results identify a noncanonical IL-1β-maturation pathway as a potential therapeutic target to combat microglia-induced neuronal dysfunction in CKD and possibly other peripheral diseases.
Authors
- Shihai Jiang (ORCID: https://orcid.org/0000-0002-0559-6160)
- Ingo Bechmann (ORCID: https://orcid.org/0000-0002-6805-1555)
- Akash Mathew (ORCID: https://orcid.org/0000-0002-3210-9479)
- Silke Zimmermann (ORCID: https://orcid.org/0000-0001-9644-8907)
- Bilal N. Sheikh (ORCID: https://orcid.org/0000-0002-1970-6236)
- Ahmed Elwakiel (ORCID: https://orcid.org/0000-0001-6784-8370)
- Nora Klöting (ORCID: https://orcid.org/0000-0002-7625-7254)
- Rajiv Rana (ORCID: https://orcid.org/0000-0002-3178-6347)
- Olga Bondareva (ORCID: https://orcid.org/0000-0001-6786-4792)
- Berend Isermann (ORCID: https://orcid.org/0000-0003-0714-6160)
- Jürgen Goldschmidt (ORCID: https://orcid.org/0000-0002-6986-9914)
Institutions
- Helmholtz Zentrum München (DE)
- University Hospital Leipzig (DE)
- Leipzig University (DE)
- Leibniz Institute for Neurobiology (DE)
Publication Details
- Journal
- Nephrology Dialysis Transplantation
- Published
- 2024-11-04
- DOI
- https://doi.org/10.1093/ndt/gfae239
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutscher Akademischer Austauschdienst
- Deutsche Forschungsgemeinschaft