An innovative integration of high-resolution synchrotron x-ray laminography fluorescence imaging

Computed laminography has become a popular tool to achieve high spatial resolution in three-dimensional imaging of flat, laterally extended objects. This study explores the synergy of synchrotron full-field micro-computed and scanning x-ray fluorescence laminography imaging, along with efficient data analysis software, to enhance x-ray imaging capabilities at beamlines 2-BM and 2-ID-E of the Advanced Photon Source at Argonne National Laboratory. We discuss the advantages of laminography imaging and demonstrate examples of laminography data acquisition and reconstruction for a flat mouse bone section measured at both beamlines. Reconstructed data provided structural information from the full-field micro-computed laminography measurements and elemental distribution from the fluorescence laminography measurements. Dragonfly ORS software was used to produce high-quality interactive volume and multichannel visualizations, facilitating the analysis of the 3D reconstructed data. The proposed integration of these two modalities for efficient structural and elemental analyses of samples holds the potential for substantial advancements in imaging technology.

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Publication Details

Published
2024-11-04
DOI
https://doi.org/10.1117/12.3028127
Primary Topic
Medical Imaging Techniques and Applications
Type
article
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article

An innovative integration of high-resolution synchrotron x-ray laminography fluorescence imaging

Fabricio Marin, Olga Antipova, Viktor Nikitin, Pei-Tzu Lee
Medical Imaging Techniques and Applications
article

An innovative integration of high-resolution synchrotron x-ray laminography fluorescence imaging

Fabricio Marin, Olga Antipova, Viktor Nikitin, Pei-Tzu Lee
article en

Abstract

Computed laminography has become a popular tool to achieve high spatial resolution in three-dimensional imaging of flat, laterally extended objects. This study explores the synergy of synchrotron full-field micro-computed and scanning x-ray fluorescence laminography imaging, along with efficient data analysis software, to enhance x-ray imaging capabilities at beamlines 2-BM and 2-ID-E of the Advanced Photon Source at Argonne National Laboratory. We discuss the advantages of laminography imaging and demonstrate examples of laminography data acquisition and reconstruction for a flat mouse bone section measured at both beamlines. Reconstructed data provided structural information from the full-field micro-computed laminography measurements and elemental distribution from the fluorescence laminography measurements. Dragonfly ORS software was used to produce high-quality interactive volume and multichannel visualizations, facilitating the analysis of the 3D reconstructed data. The proposed integration of these two modalities for efficient structural and elemental analyses of samples holds the potential for substantial advancements in imaging technology.

Argonne National Laboratory (US)
Openalex Percentile: Top 67%
Medical Imaging Techniques and Applications
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An innovative integration of high-resolution synchrotron x-ray laminography fluorescence imaging — Fabricio Marin, Olga Antipova, et al. · (2024) | TGRS Research Map | TGRS