Astaxanthin mediated repair of tBHP-Induced cellular injury in chondrocytes
Astaxanthin effectively mitigates oxidative stress and inflammation in chondrocytes via the circ-HP1BP3/miR-139-5p/SOD1 pathway. The development of AST-loaded microspheres offers a novel and promising approach for osteoarthritis therapy, potentially extending to osteoarthritis treatment.
Authors
- Yaojun Lu
- Wen-Wei Liang (ORCID: https://orcid.org/0000-0001-7700-8973)
- Hao Wu (ORCID: https://orcid.org/0000-0003-1269-7354)
- Gang Liu (ORCID: https://orcid.org/0000-0003-4804-1787)
- Wei Chen (ORCID: https://orcid.org/0000-0001-5451-6430)
- Chunhui Zhu (ORCID: https://orcid.org/0000-0001-8947-463X)
- Qin Yao (ORCID: https://orcid.org/0000-0003-4485-4545)
- Weibo Zhou
Institutions
- Changzhou No.2 People's Hospital (CN)
- Jiangsu Province Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Redox Report
- Published
- 2024-11-04
- DOI
- https://doi.org/10.1080/13510002.2024.2422271
- Citations
- 5
- Primary Topic
- Antioxidant Activity and Oxidative Stress
- Type
- article
- Field-Weighted Citation Impact
- 1.11
Funders
- Project on Maternal and Child Health Talents of Jiangsu Province
- Tianjin Municipal Transportation Commission Science and Technology Development Plan Project