Effect of intravitreal injection of anti-interleukin (IL)-6 antibody in experimental autoimmune uveitis in mice
Intravitreal administration of anti-IL-6 treatment notably mitigates experimental autoimmune uveitis in mice, both functionally and clinically. Further investigations are warranted to assess the potential of intravitreal anti-IL-6 therapy as a treatment option for non-infectious uveitis in humans.
Authors
- Christoph Ehlken (ORCID: https://orcid.org/0000-0001-7388-7173)
- Jan Tode (ORCID: https://orcid.org/0000-0003-2422-532X)
- Stefan Rose‐John (ORCID: https://orcid.org/0000-0002-7519-3279)
- Kristin Hösel (ORCID: https://orcid.org/0000-0003-3399-4411)
- Johann Roider
- Büsra Chasan
Institutions
- Christian-Albrechts-Universität zu Kiel (DE)
- Ophthalmology Clinic (DE)
- Hannover Re (Germany) (DE)
- Clinical Research Center Kiel (DE)
Publication Details
- Journal
- Journal of Ophthalmic Inflammation and Infection
- Published
- 2024-11-04
- DOI
- https://doi.org/10.1186/s12348-024-00441-x
- Citations
- 1
- Primary Topic
- Ocular Diseases and Behçet’s Syndrome
- Type
- article
- Field-Weighted Citation Impact
- 0.54