The Immunomodulatory Effect of Different FLT3 Inhibitors on Dendritic Cells
Our results suggest different immunosuppressive effects of these three FLT3i and may, therefore, provide an additional rationale for optimal maintenance therapy after alloHSCT of FLT3-positive AML patients to prevent infectious complications and GvHD mediated by DCs.
Authors
- Peter Brossart (ORCID: https://orcid.org/0009-0002-9324-5527)
- Sebastian Schlaweck (ORCID: https://orcid.org/0000-0002-3239-5444)
- Benjamin V. Becker (ORCID: https://orcid.org/0000-0002-8557-8797)
- Annkristin Heine (ORCID: https://orcid.org/0000-0002-5298-9880)
- Alea Radcke
- Sascha Kampmann
Institutions
- University of Bonn (DE)
- University Hospital Bonn (DE)
- Düsseldorf University Hospital (DE)
- Bundeswehrzentralkrankenhaus Koblenz (DE)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- Cancers
- Published
- 2024-11-04
- DOI
- https://doi.org/10.3390/cancers16213719
- Citations
- 6
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 2.73
Funders
- Deutsche Forschungsgemeinschaft
- Deutsche Krebshilfe