Menopausal hormone therapy and incidence, mortality, and survival of breast cancer subtypes: a prospective cohort study

Our study suggests that MHT use increases the risk of incident and fatal overall and luminal A-like, and incident luminal B-like breast cancer but does not decrease overall survival among patients with breast cancer. Further research is needed to elucidate the mechanisms underlying MHT use and breast cancer lethality, and to explore whether MHT use among patients with TNBC is indeed free from harm.

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Institutions

Publication Details

Journal
Breast Cancer Research
Published
2024-11-04
DOI
https://doi.org/10.1186/s13058-024-01897-4
Citations
7
Primary Topic
Estrogen and related hormone effects
Type
article
Field-Weighted Citation Impact
3.85

Funders

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article

Menopausal hormone therapy and incidence, mortality, and survival of breast cancer subtypes: a prospective cohort study

Marit Busund, Eiliv Lund, Giske Ursin, S Chen et al.
7 citations
Breast Cancer Research
Estrogen and related hormone effects
3.85
article

Menopausal hormone therapy and incidence, mortality, and survival of breast cancer subtypes: a prospective cohort study

Marit Busund, Eiliv Lund, Giske Ursin, S Chen, Charlotta Rylander
article en
7 citations

Abstract

Our study suggests that MHT use increases the risk of incident and fatal overall and luminal A-like, and incident luminal B-like breast cancer but does not decrease overall survival among patients with breast cancer. Further research is needed to elucidate the mechanisms underlying MHT use and breast cancer lethality, and to explore whether MHT use among patients with TNBC is indeed free from harm.

Breast Cancer ResearchVol. 26(1)
University of Southern California (US), Norwegian Institute of Public Health (NO), University of Oslo (NO), Cancer Registry of Norway (NO), UiT The Arctic University of Norway (NO)
Universitetet i Tromsø
Good health and well-being
Openalex Percentile: Top 6%
Estrogen and related hormone effects
3.85
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