A Comparative Evaluation of Efficacy of Local Infiltration of Sodium Bicarbonate Buffered Local Anesthesia with Epinephrine Vs Non-Buffered La with Epinephrine: A Clinical Study

Background: The aim of the study was to compare the efficacy of local infiltration of sodium bicarbonate buffered local anaesthesia with epinephrine vs non- buffered local anaesthesia with epinephrine.  Method: Patients having periapical infection in the maxillary anterior and premolar region were selected for the study. A total of 50 patients were included in the study. In group A, 8.4% sodium bicarbonate buffered 2% Lignocaine with 1:80,000 adrenaline was used for local infiltration for extraction. In group B, 2% Lignocaine with 1:80,000 adrenaline (non-buffered) was used for local infiltration for extraction. The onset of anesthesia, was compared between group A and group B. Data was tabulated and statistical analysis was carried out using paired t-test.  Result: The inter-group difference in onset of anesthesia,was assessed using paired t-test and highly significant difference was found between group A and group B (p≤0.05).  Conclusion: Significant improvement seen in onset of anesthesia and duration of anesthesia.