Tracing ALS Degeneration: Insights from Spinal Cord and Cortex Transcriptomes
These results highlight the distinct and shared molecular disruptions in ALS, emphasizing the critical roles of immune response and metabolic dysfunction in neuronal degeneration. Targeting these pathways may provide new therapeutic avenues to combat neurodegeneration and preserve neuronal health.
Authors
- Y‐h. Taguchi (ORCID: https://orcid.org/0000-0003-0867-8986)
- M. Michael Gromiha (ORCID: https://orcid.org/0000-0002-1776-4096)
- Nela Pragathi Sneha (ORCID: https://orcid.org/0000-0002-7978-0403)
- S. Akila Parvathy Dharshini
Institutions
- Indian Institute of Technology Madras (IN)
- Chuo University (JP)
Publication Details
- Journal
- Genes
- Published
- 2024-11-02
- DOI
- https://doi.org/10.3390/genes15111431
- Citations
- 3
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 1.11
Funders
- Indian Institute of Technology Madras
- Ministry of Education, India
- Division of Human Resource Development