Correlation of factor XIII subunit A with factor XIII activity in a population of parturient women
The correlation of factor XIII activity with factor XIII antigen (subunit A) in a large real-world sample as well as an association of prepartum factor XIII antigen and postpartum blood loss is observed. Factor XIII antigen determination, a highly automatable test, could be useful in emergency situations such as a PPH (as well as other bleeding situations) if the determination of factor XIII activity is not possible. To evaluate whether FXIII replenishment reduces blood loss is the focus of ongoing studies.
Authors
- Wolfgang Korte (ORCID: https://orcid.org/0000-0003-0076-5022)
- J.J. Burgi (ORCID: https://orcid.org/0000-0003-4210-0061)
- Nicole Ochsenbein‐Kölble (ORCID: https://orcid.org/0000-0002-7691-965X)
- Marie Louise Frevert (ORCID: https://orcid.org/0000-0002-6497-7051)
- R. Brun (ORCID: https://orcid.org/0000-0002-5638-3405)
- Torsten Hothorn (ORCID: https://orcid.org/0000-0001-8301-0471)
- Christian Haslinger (ORCID: https://orcid.org/0000-0003-3344-9480)
- Matthias Rösslein
Institutions
- University of Zurich (CH)
- University of St.Gallen (CH)
- University Hospital of Zurich (CH)
- Zurich University of Teacher Education (CH)
- Swiss Federal Laboratories for Materials Science and Technology (CH)
Publication Details
- Journal
- Archives of Gynecology and Obstetrics
- Published
- 2024-11-04
- DOI
- https://doi.org/10.1007/s00404-024-07799-2
- Primary Topic
- Blood properties and coagulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- CSL Behring
- Universität Zürich
- Universitätsspital Zürich