Comparing the Sedative Effect of Dexmedetomidine and Propofol in Mechanically Ventilated Patients Using Salivary Alpha-Amylase as a Stress Marker: A Randomized Open-Label Trial
Dexmedetomidine demonstrated superior stress-reducing effects compared to propofol in MV patients, as evidenced by lower SAA levels and improved hemodynamic stability. The shorter duration of MV in the dexmedetomidine group further suggests potential clinical benefits of its use in managing stress in MV patients.
Authors
- Abdallah Elabd Hassan (ORCID: https://orcid.org/0009-0005-4083-3407)
- Abdelkarem Hussini Ismail Alsayed
- Rehab Abd El Fattah Helal
- Mohammed Said ElSharkawy (ORCID: https://orcid.org/0000-0003-0814-6728)
- Reda Khalil Abdelrahman
- Mohammed Saad (ORCID: https://orcid.org/0009-0006-4244-9377)
- Ahmed Mohamed Ibrahim
- Asmaa Abdelbadie
- Ismail Ahmed Elzoughari
Institutions
- Al-Azhar University (EG)
- King Abdulaziz University (SA)
- Tanta University (EG)
- Nahda University (EG)
- King Abdulaziz Hospital (SA)
Publication Details
- Journal
- Anesthesiology and Pain Medicine
- Published
- 2024-10-27
- DOI
- https://doi.org/10.5812/aapm-149364
- Citations
- 3
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.27