The causal nexus between diverse smoking statuses, potential therapeutic targets, and NSCLC: insights from Mendelian randomization and mediation analysis
This study, integrating bioinformatics and MR analysis, identified three potential predictive targets as mediators to investigate the causal relationships between different smoking statuses and NSCLC through potential therapeutic targets, providing new insights for the treatment and prevention of NSCLC.
Authors
- Shaodan Hu (ORCID: https://orcid.org/0000-0003-1177-0679)
- Li Shi (ORCID: https://orcid.org/0009-0005-3809-7260)
- Tong Wu (ORCID: https://orcid.org/0000-0002-2296-3380)
- Zhiyu Tian (ORCID: https://orcid.org/0000-0002-5822-976X)
- Feng Sun
- Zhenghua Cao (ORCID: https://orcid.org/0009-0008-2827-9775)
- Huan Ding (ORCID: https://orcid.org/0000-0003-3894-3875)
- Zhuo Feng
- Shengkun Zhao
Institutions
- Changchun University of Chinese Medicine (CN)
- Suzhou Traditional Chinese Medicine Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2024-11-04
- DOI
- https://doi.org/10.3389/fonc.2024.1438851
- Citations
- 4
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- People's Government of Jilin Province