Expanding the role of metoclopramide in Tardive Dyskinesia: A case report

Tardive dyskinesia is a medication-induced movement disorder commonly caused by the blockade or depletion of dopamine in the basal ganglia, seen mostly in the psychiatric setting following prolonged use of antipsychotic medications. It is also reported in other settings where patients receive non-antipsychotic medications. The prevalence of tardive dyskinesia varies across age, gender, and race, with women of middle age being more prone to develop tardive dyskinesia more than men. Therefore, we report a case of tardive dyskinesia, post-delivery, in an African woman, who received metoclopramide as part of premedication for spinal anesthesia for an emergency cesarean delivery. The debriefing period following the resolution of the symptoms offered a clue to prior utilization of metoclopramide for the treatment of hyperemesis gravidarum as provided by the patient's family. Hence, fulfilling the diagnostic criteria of prolong usage of the implicating agent.

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Journal
Psychiatry Research Case Reports
Published
2024-11-03
DOI
https://doi.org/10.1016/j.psycr.2024.100238
Primary Topic
Parkinson's Disease and Spinal Disorders
Type
article
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article

Expanding the role of metoclopramide in Tardive Dyskinesia: A case report

Omosumwen Ede, V Ugwu, Ogochukwu Agazie, Evaristus Chino Ezema et al.
Psychiatry Research Case Reports
Parkinson's Disease and Spinal Disorders
article

Expanding the role of metoclopramide in Tardive Dyskinesia: A case report

Omosumwen Ede, V Ugwu, Ogochukwu Agazie, Evaristus Chino Ezema, Ngozi T Akueme, John Mmaduabuchi, Valentine Keke, Chinenye Loveth Aleke, Emmanuel Chiebuka, Ndukaku Ogbonna, Sanmi Michael, Omotola Emmanuel, Nnenna Bessie Emejuru, Precious Okpechi, Maureen Obi
article en

Abstract

Tardive dyskinesia is a medication-induced movement disorder commonly caused by the blockade or depletion of dopamine in the basal ganglia, seen mostly in the psychiatric setting following prolonged use of antipsychotic medications. It is also reported in other settings where patients receive non-antipsychotic medications. The prevalence of tardive dyskinesia varies across age, gender, and race, with women of middle age being more prone to develop tardive dyskinesia more than men. Therefore, we report a case of tardive dyskinesia, post-delivery, in an African woman, who received metoclopramide as part of premedication for spinal anesthesia for an emergency cesarean delivery. The debriefing period following the resolution of the symptoms offered a clue to prior utilization of metoclopramide for the treatment of hyperemesis gravidarum as provided by the patient's family. Hence, fulfilling the diagnostic criteria of prolong usage of the implicating agent.

Psychiatry Research Case ReportsVol. 3(2)
University of Nigeria (NG), Enugu State University of Science and Technology (NG), Emory Healthcare (US), Westat (United States) (US), St. George's University (GD), Imo State University (NG), Benue State University (NG), University of Lagos (NG), Health Net (US), Virginia University of Lynchburg (US), Federal Medical Centre (NG), Children's Healthcare of Atlanta (US), St. Vincent and the Grenadines Community College (VC), SalvageBlue (Saint Vincent and the Grenadines) (VC), Obafemi Awolowo University Teaching Hospitals Complex (NG), Obafemi Awolowo University (NG), College of New Rochelle (US), Olusegun Agagu University of Science and Technology (NG)
Gender equality
Openalex Percentile: Top 70%
Parkinson's Disease and Spinal Disorders
DOIOpen Access PDFOpenAlex
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