Rauvolfia vomitoria phenol extract relieves pentylenetetrazol-induced seizures in Swiss mice and protects some temporal lobe structures
Thus, R. vomitoria phenol extract showed promising results against seizures and potential for general brain protection, suggesting that the anticonvulsant property of R. vomitoria may be attributed to its phenol constituent. More studies are needed to delineate the mechanisms of its action.
Authors
- Christopher C. Mbadugha (ORCID: https://orcid.org/0000-0003-1483-8616)
- Moses B. Ekong (ORCID: https://orcid.org/0000-0002-2737-2918)
- Rosemary B. Bassey (ORCID: https://orcid.org/0000-0001-9105-6912)
- Aniekan Imo Peter (ORCID: https://orcid.org/0000-0002-1155-6368)
- Jude E. Okokon (ORCID: https://orcid.org/0000-0002-2587-4535)
- Okokon O. Bassey (ORCID: https://orcid.org/0009-0009-8683-0454)
- M. I. Akpanabiatu (ORCID: https://orcid.org/0000-0003-3639-5203)
- D. V. K. Samuel (ORCID: https://orcid.org/0009-0007-1038-5409)
- Deborah I. Ebeh (ORCID: https://orcid.org/0009-0006-1489-5476)
- Godslove D. Usukuma
Institutions
- University of Uyo (NG)
- Donald & Barbara Zucker School of Medicine at Hofstra/Northwell (US)
Publication Details
- Journal
- Acta Epileptologica
- Published
- 2024-11-04
- DOI
- https://doi.org/10.1186/s42494-024-00183-2
- Citations
- 1
- Primary Topic
- Medicinal Plants and Neuroprotection
- Type
- article
- Field-Weighted Citation Impact
- 0.72
Funders
- International Brain Research Organization
- Tertiary Education Trust Fund
- International Society for Neurochemistry