Oral manifestations as the first sign of Granulomatosis with polyangiitis – A case report

Granulomatosis with polyangiitis (GPA) is a rare and potentially life-threatening systemic vasculitis characterized by necrotizing granulomatous inflammation of small- to medium-sized vessels. This case reports a unique case of a 38-year-old woman who presents with strawberry gingivitis as the first sign of GPA. The patient was seen in different departments and was finally diagnosed with GPA after a delay of 3 months from the first sign of gingival lesions. The patient did not suffer from any serious complications of this delay besides from tinnitus, reduced hearing and sensitivity to sound. The present case highlights the importance of early recognition of the oral manifestations of GPA in order to start the comprehensive treatment timely for successful outcome.

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Publication Details

Journal
Medical Reports
Published
2024-11-03
DOI
https://doi.org/10.1016/j.hmedic.2024.100129
Primary Topic
Vasculitis and related conditions
Type
article
Field-Weighted Citation Impact
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article

Oral manifestations as the first sign of Granulomatosis with polyangiitis – A case report

Ulrik Ørsø Andersen, Preben Homøe, Yousra Akhlef
Medical Reports
Vasculitis and related conditions
article

Oral manifestations as the first sign of Granulomatosis with polyangiitis – A case report

Ulrik Ørsø Andersen, Preben Homøe, Yousra Akhlef
article en

Abstract

Granulomatosis with polyangiitis (GPA) is a rare and potentially life-threatening systemic vasculitis characterized by necrotizing granulomatous inflammation of small- to medium-sized vessels. This case reports a unique case of a 38-year-old woman who presents with strawberry gingivitis as the first sign of GPA. The patient was seen in different departments and was finally diagnosed with GPA after a delay of 3 months from the first sign of gingival lesions. The patient did not suffer from any serious complications of this delay besides from tinnitus, reduced hearing and sensitivity to sound. The present case highlights the importance of early recognition of the oral manifestations of GPA in order to start the comprehensive treatment timely for successful outcome.

Medical ReportsVol. 8
Zealand University Hospital (DK), Zealand University Hospital Køge (DK)
Zero hunger
Openalex Percentile: Top 64%
Vasculitis and related conditions
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