Histological Study Of The Effect Of Nano Silver And Nano Zinc On The Healing Of Traumatic Ulcer In The Oral Mucosa

Background: Nanoparticles have been under consideration for usage in healthcare and the field of wound healing because of their cost-effectiveness, small size, stability and safety. In wound healing, nanoparticles are evaluated based on three key criteria: their function as delivery vehicles, role in the repair process and antimicrobial properties. Because of these characteristics, metal nanoparticles like gold, silver, copper, and zinc are excellent candidates for use in the wound bed and for incorporation into dressings. Objectives: To study the healing of experimentally induced traumatic ulcers in the oral mucosa of Albino rats by using topically Nano silver and Nano zinc. Materials and methods: we used adult male albino rats which are 40 in number and were separated into four groups, 10 rats for each group: Group I: was a normal group. Group II: the ulcer was left without treatment. Group III: the ulcer was treated by twice daily topical application of Nano silver solution. Group IV: the ulcer was treated by twice daily topical application of Nano zinc solution. Each group except Group I divided into two subgroups: subgroup 1 sacrificed after 7 days and subgroup 2 sacrificed after 14 days.  Results: wound healing is completed after 14 days while the usage of Nano medicine improve healing. Conclusion: Nano silver is antimicrobial agent; this prevent wound infection and that is why wound healing improved.