Role of Adherence to Treatment in the Correction of the Risk of Cardiovascular Complications in Patients with Arterial Hypertension with Accompanying Diabetes Mellitus

Introduction. The presence of diabetes mellitus (DM), its duration, and the severity of the course significantly affect the degree of damage to target organs and the risk of cardiovascular complications (CVD) in patients with arterial hypertension (AH). It is also known that the effectiveness of the correction of the risks of CVD is influenced not only by the optimization of disease therapy but also by the adherence of patients to treatment, which created the prerequisites for this study. The aim of the study. To investigate the role of adherence to treatment in the correction of the risk of cardiovascular complications in patients with arterial hypertension with accompanying diabetes mellitus. Materials and methods. The study included 120 patients with a stable course of stage II hypertension of 1st-2nd degrees with concomitant type 2 diabetes with the disease duration of more than 1 year. Results. After 3 months of observation, in most patients with good adherence to treatment the target level of BP (in 78.3 ± 5.3 %) and the target level of HvA1c (in 56.7 ± 6.4 %) and a decrease in the 10-year risk of cardiovascular disease according to the SCORE2 diabetes scale (from 34.1 ± 3.7 points to 27.3 ± 3.8 points, p < 0.05) were achieved. The Pearson correlation coefficient between the SCORE2 diabetes risk indicator and the adherence to treatment indicator was: r = -0.916, p < 0.05, which indicates a close feedback relationship. Conclusions. High adherence to treatment in the majority of patients with hypertension with accompanying diabetes allows them to achieve the target levels of blood pressure and glycemia, significantly reduce the risk index of cardiovascular complications, which has a close inverse correlation with the adherence of patients to treatment.