Docetaxel Induced Nail Changes: A Case Report

Introduction: Docetaxel is chemotherapeutic drug belongs to taxane classification, used in the treatment of various type of cancers such as breast, stomach, head and neck. Docetaxel encounters various Adverse Drug Reactions among which nail changes are commonly observed i.e nail bed purpura, onycholysis, nail pigmentation, splinter hemorrhage have been reported. Worldwide incidence of patients developing nail changes range from 0% to 44%. Case presentation: A 41 Years old female patient came to oncology daycare with nail dis-colouration. she was on treatment with docetaxel 3rd cycle chemotherapy for breast cancer. on physical examination, all her nails revealed the dis-coloration which was gradually increasing. Conclusion: Several research studies shown similar adverse drug reaction with prolonged use of docetaxel and care should be taken in identifying and educating the patient in dos & don?t s of nail care as it hinder their adherence to the medication.