Analysis of the Correlation between In-hospital Adverse Events and Transcatheter Aortic Valve Replacement Outcomes

Transcatheter aortic valve replacement (TAVR) has been recommended as the standard treatment for elderly patients with severe aortic stenosis (AS) and those at increased risk for conventional surgical procedures. Recently, TAVR has been recognized as the treatment of choice for intermediate-risk patients or even low-risk populations with AS. Our study aimed to identify factors influencing adverse events after TAVR procedures. This single-center, retrospective cohort study involved patients with severe AS treated with TAVR from 2016 to 2019. The patient’s electronic medical record was reviewed, and those with valve-in-valve replacements and missing demographical data were excluded. We analyzed risk factors related to in-hospital adverse outcomes after the TAVR procedure. Among 953 screened patients, 889 were included in the study. The complication rates were relatively low. Factors that significantly influenced the outcome included age, chronic kidney disease (CKD), dialysis, mitral stenosis, Katz test for frailty, surgical risk score, and calculated operability. Multivariate logistic regression analysis showed that only CKD predicts the likelihood of the composite adverse outcome in TAVR patients during hospitalization. Our study showed that TAVR is an effective and safe option for aortic valve replacement. Perioperative complications depend on different risk factors, particularly CKD, and the results of the Katz test. Identification of risk factors influencing the TAVR outcome is crucial to prevent perioperative complications and mortality.