A Single Cell Transcriptomic Fingerprint of Stressed Premature, Imbalanced Differentiation of Embryonic Stem Cells
Hyperosmotic stress, and other toxicological stresses, like drugs with active ingredient RA, may cause premature, lineage imbalance, resulting in miscarriages or birth defects.
Authors
- Wen Tang (ORCID: https://orcid.org/0000-0003-3710-9029)
- Ximena Ruden
- Elizabeth E. Puscheck
- Steven J. Korzeniewski (ORCID: https://orcid.org/0000-0002-8895-6052)
- Teya Marben
- Hao Feng
- Awoniyi O. Awonuga (ORCID: https://orcid.org/0000-0002-0864-5394)
- Douglas M. Ruden (ORCID: https://orcid.org/0000-0002-0070-437X)
- Daniel A Rappolee (ORCID: https://orcid.org/0000-0001-8526-5953)
- Aditi Singh (ORCID: https://orcid.org/0000-0002-6539-4544)
Institutions
- Wayne State University (US)
- Case Western Reserve University (US)
- University of Detroit Mercy (US)
Publication Details
- Journal
- Birth Defects Research
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1002/bdr2.2409
- Citations
- 3
- Primary Topic
- Pluripotent Stem Cells Research
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- National Institute of Environmental Health Sciences