Plasma exosomes may mediate the development of lupus nephritis in patients with systemic lupus erythematosus
Our research indicates that the abundant presence of miR-20b-5p and the depletion of miR-181a-2-3p in plasma exosomes of SLE patients may mediate the promotion of apoptosis and autophagy in HK2 cells, thereby causing kidney damage and the development of LN.
Authors
- Yinde Xu
- Xiaolan Li (ORCID: https://orcid.org/0000-0001-8431-3212)
- Jianjun Ye
- Jie Liu (ORCID: https://orcid.org/0000-0002-4530-1443)
- Yun Zhu (ORCID: https://orcid.org/0009-0003-5193-5180)
- Yuanju Liu
Institutions
- Kunming Medical University (CN)
Publication Details
- Journal
- Lupus
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1177/09612033241298047
- Citations
- 2
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- National Natural Science Foundation of China