Short‐chain fatty acids enhance muscle mass and function through the activation of mTOR signalling pathways in sarcopenic mice
This study demonstrated that bacterial metabolites SCFAs could attenuate age-related muscle loss and dysfunction, and protein synthesis-related mTOR signalling pathways were involved both in vivo and in vitro.
Authors
- Wing‐Hoi Cheung (ORCID: https://orcid.org/0000-0003-3247-8255)
- Ronald Man Yeung Wong (ORCID: https://orcid.org/0000-0001-5615-6627)
- Qianjin Wang (ORCID: https://orcid.org/0000-0003-1474-0918)
- Pui Yan Wong (ORCID: https://orcid.org/0000-0001-6513-1843)
- Can Cui (ORCID: https://orcid.org/0000-0001-9328-4521)
- Ning Zhang (ORCID: https://orcid.org/0000-0002-9513-9288)
- Tao Huang (ORCID: https://orcid.org/0009-0007-8196-2090)
- Chaoran Liu
- Hei Yuet Wong
Institutions
- Chinese University of Hong Kong (HK)
Publication Details
- Journal
- Journal of Cachexia Sarcopenia and Muscle
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1002/jcsm.13573
- Citations
- 46
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 15.02