Cutaneous Sarcoidosis Case Report

Cutaneous and systemic sarcoidosis case report Sarcoidosis is an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands. In people with sarcoidosis, abnormal masses or nodules (called granulomas) consisting of inflamed tissues form in certain organs of the body. These granulomas may alter the normal structure and possibly the function of the affected organ(s). Objective: To identify systemic and cutaneous disease in human body with bone marrow proliferation. Patients and Methods: 54 years old man patient complained of fever and night sweats. He was missed diagnosed in Cairo by oncologist as diffuse large B cell lymphoma patient since 2007 due to involvement liver and lymph nodes and he received treatment with Gemser drug and he complete remission from liver damage. At 2015 complained of night sweats; fever and loss of weight and high coup and rheumatic pain miss diagnosed as tuberculosis T B in Jordan and he received treatment for one year without improvement. I received the patient in 2018 started appeared erythematous papule nodular skin eruptions in his body I revised all his previous investigations. CBC, Bone marrow biopsy and aspiration, liver biopsy, hilar lymph node biopsy skin biopsy, immunohistochemical cytology zeal Nelson stain-vet, PCR-VE, tuberculin test -vet ACE angiotensin converting enzyme and liver function test were diagnostic plain chest or-ay, ultrasound for liver. Results: The clinical data and investigations showed the patient had non Caseating necrosis inflammatory granuloma in his thoracic lymph nodes and liver and skin most probably systemic and cutaneous sarcoidosis. Conclusion: Arcoidosis is unknown etiology disease and treated with methotrexate and prednisolone orally with monitoring follow up.