ROLE OF SMALL VESSEL THROMBO-EMBOLECTOMY IN LOWER LIMB SALVAGE AND ITS CLINICO PATHOLOGICAL SPECTRUM IN ACUTE LIMB ISCHEMIA

Acute limb ischemia (ALI) is a vascular emergency where prompt intervention is crucial to salvage the limb. The standard treatment window is within 6 hours; beyond this period, the limb is presumed to suffer irreversible ischemic damage. However, surgical interventions like retrograde thrombo-embolectomy offer hope for limb salvage even in delayed presentations. This study investigates the efficacy of retrograde thrombo-embolectomy in small distal vessel occlusions due to thrombus or embolus in patients presenting after the 12-hour mark. Objective: To report the patients who presented to us beyond the 6-hours mark, beyond which the limb is presumed to have developed irreversible ischemic changes. The efficacy of retrograde thrombo-embolectomy in distal small vessel occlusion secondary to thrombus or embolus in delayed presentation of ALI was also evaluated. Methods: Thirty-five cases presented with acute limb ischemia for more than 12 hours. All Rutherford Grade IIa, IIb were included in the study. A prospective cross-sectional study was conducted and intra-operative findings, outcomes, post-operative complications were noted. All selected patients were operated by open surgery approach consisting of CFA thrombectomy and retrograde PTA/ATA Thrombo-embolectomy at ankle depending on thrombus site. Results: The study demonstrated a 97.1% success rate in limb salvage and functionality over 6 months follow-up. One patient had a major complication of re-thrombosis for which a repeat procedure was done. Four patients developed minor complications such as wound infection, ray amputation, needing wound debridement. Conclusion: Surgical intervention is possible for acute ischemic limb with delayed presentation (>12 hour). An open surgical approach is a safe and reliable option in such patients. However, further research is needed with a wider study population to actually see benefits of surgical intervention in delayed ALI presentation.

Authors

Institutions

Publication Details

Journal
Biological and Clinical Sciences Research Journal
Published
2024-10-31
DOI
https://doi.org/10.54112/bcsrj.v2024i1.1187
Primary Topic
Peripheral Artery Disease Management
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

ROLE OF SMALL VESSEL THROMBO-EMBOLECTOMY IN LOWER LIMB SALVAGE AND ITS CLINICO PATHOLOGICAL SPECTRUM IN ACUTE LIMB ISCHEMIA

Imana Sadiq, Aqsa Mushtaq, Moiz A. Nasir
Biological and Clinical Sciences Research Journal
Peripheral Artery Disease Management
article

ROLE OF SMALL VESSEL THROMBO-EMBOLECTOMY IN LOWER LIMB SALVAGE AND ITS CLINICO PATHOLOGICAL SPECTRUM IN ACUTE LIMB ISCHEMIA

Imana Sadiq, Aqsa Mushtaq, Moiz A. Nasir
article en

Abstract

Acute limb ischemia (ALI) is a vascular emergency where prompt intervention is crucial to salvage the limb. The standard treatment window is within 6 hours; beyond this period, the limb is presumed to suffer irreversible ischemic damage. However, surgical interventions like retrograde thrombo-embolectomy offer hope for limb salvage even in delayed presentations. This study investigates the efficacy of retrograde thrombo-embolectomy in small distal vessel occlusions due to thrombus or embolus in patients presenting after the 12-hour mark. Objective: To report the patients who presented to us beyond the 6-hours mark, beyond which the limb is presumed to have developed irreversible ischemic changes. The efficacy of retrograde thrombo-embolectomy in distal small vessel occlusion secondary to thrombus or embolus in delayed presentation of ALI was also evaluated. Methods: Thirty-five cases presented with acute limb ischemia for more than 12 hours. All Rutherford Grade IIa, IIb were included in the study. A prospective cross-sectional study was conducted and intra-operative findings, outcomes, post-operative complications were noted. All selected patients were operated by open surgery approach consisting of CFA thrombectomy and retrograde PTA/ATA Thrombo-embolectomy at ankle depending on thrombus site. Results: The study demonstrated a 97.1% success rate in limb salvage and functionality over 6 months follow-up. One patient had a major complication of re-thrombosis for which a repeat procedure was done. Four patients developed minor complications such as wound infection, ray amputation, needing wound debridement. Conclusion: Surgical intervention is possible for acute ischemic limb with delayed presentation (>12 hour). An open surgical approach is a safe and reliable option in such patients. However, further research is needed with a wider study population to actually see benefits of surgical intervention in delayed ALI presentation.

Biological and Clinical Sciences Research JournalVol. 2024(1)
Mayo Hospital (PK)
Openalex Percentile: Top 63%
Peripheral Artery Disease Management
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.