Successful treatment of two capillary psoriasis patients with cream containing Plinia cauliflora: a case report

Psoriasis is a chronic inflammatory skin condition that can affect any area of the body. It is characterized by reddish, scaling and erythematous lesions, being psoriasis vulgaris or plaque psoriasis the main form of clinical presentation of this disease. The existence of several adverse effects associated with the drugs already used in the treatment of this dermatosis stimulates studies focusing on the development of alternative therapies for its treatment. Plinia cauliflora (jabuticaba) is rich in flavonoids and has shown to have anti-inflammatory, antioxidant, antibacterial and anti-proliferative actions. The aim of this study was to evaluate the topical effect of P. cauliflora on skin lesions resulting from plaque psoriasis through case reports of six patients with psoriasis vulgaris who had lesions on the scalp or on both elbows and had not used topical or oral corticoids for at least four weeks. The selected regions were treated with P. cauliflora cream for four weeks and their evolution was followed through weekly photographs. P. cauliflora cream showed to have an anti-psoriatic effect, being observed in the volunteers a mean reduction of erythema in 33.3%, infiltration in 50% and local symptoms, measured through the Visual Analog Scale in 33.9%. Despite the promising effects of P. cauliflora, clinical studies with a larger number of volunteers are recommended to confirm its scientific validity.