Case report of unilateral optic nerve infiltration in marginal zone B-cell lymphoma with retinal vein occlusion

This case report described a 61-year-old male patient who presented with unilateral optic nerve infiltration and retinal vein occlusion as ocular manifestations of marginal zone B-cell lymphoma (SMZL). The patient experienced sudden vision loss in his left eye, accompanied by a relative afferent pupillary defect and findings of optic disc edema, hemorrhage, and retinal ischemia upon fundus examination. The individual had a previous diagnosis of SMZL prior to the onset of ocular symptoms. Subsequent evaluations confirmed lymphoma infiltration of the left optic nerve and retinal vein occlusion. Following a month of chemotherapy, there was observed improvement in the left eye, characterized by the resolution of optic disc edema and retinal ischemia.