[Acute blindness in a patient with metformin-associated lactic acidosis].

Lactic acidosis is a rare metabolic complication that can occur in patients with diabetes mellitus type 2 who use metformin. We discuss a 79-year old woman with metformin-associated lactic acidosis (MALA) and acute kidney injury based on gastroenteritis. Patient reported acute blindness which in literature is described as a rare presentation of a metabolic acidosis (regardless of its underlying cause). Immediate treatment with hemodialysis led to improvement of the acidosis and complete recovery of the vision. It is important that patients who use metformin are instructed to consult their health care provider and/or discontinue metformin in case of intercurrent diseases.

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Journal
PubMed
Published
2024-10-24
Citations
1
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.36
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article

[Acute blindness in a patient with metformin-associated lactic acidosis].

Jacob W Bosma, Ramsha Iqbal, Stefanie Koster, Niels Hakkens et al.
1 citations
PubMed
Diabetes Treatment and Management
0.36
article

[Acute blindness in a patient with metformin-associated lactic acidosis].

Jacob W Bosma, Ramsha Iqbal, Stefanie Koster, Niels Hakkens, Rob J.L. Klaassen, Brigitta Scheerman
article en
1 citations

Abstract

Lactic acidosis is a rare metabolic complication that can occur in patients with diabetes mellitus type 2 who use metformin. We discuss a 79-year old woman with metformin-associated lactic acidosis (MALA) and acute kidney injury based on gastroenteritis. Patient reported acute blindness which in literature is described as a rare presentation of a metabolic acidosis (regardless of its underlying cause). Immediate treatment with hemodialysis led to improvement of the acidosis and complete recovery of the vision. It is important that patients who use metformin are instructed to consult their health care provider and/or discontinue metformin in case of intercurrent diseases.

PubMedVol. 168
Zaans Medisch Centrum (NL), Phoenix Contact (United States) (US)
Openalex Percentile: Top 32%
Diabetes Treatment and Management
0.36
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