[Fluorescence Quantitative PCR Detection of <i>ABL1</i> Kinase Region Mutations].
Compared with Sanger sequencing, fluorescence quantitative PCR has higher sensitivity and can screen for low-frequency <i>ABL1</i> kinase mutations in the early stage. Moreover, it can also perform relative quantitative analysis, so the method has good clinical application prospects for detecting <i>ABL1</i> mutation.
Authors
- Darren Y. Wang
- Ting Gong (ORCID: https://orcid.org/0000-0001-8877-9482)
- Yu Liu (ORCID: https://orcid.org/0000-0002-6262-1887)
- Si Li (ORCID: https://orcid.org/0009-0009-8641-0150)
- Jun Ma (ORCID: https://orcid.org/0000-0002-1137-9349)
- Huan-Chen Cheng
Institutions
- Harbin Medical University (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-10-01
- DOI
- https://doi.org/10.19746/j.cnki.issn.1009-2137.2024.05.011
- Primary Topic
- Molecular Biology Techniques and Applications
- Type
- article