[Pharmacokinetic Study of Coagulation Factor Ⅷ in Adults with Severe Hemophilia A].
There are significant individual differences in the FⅧ half-life of adult patients with severe hemophilia A. The older the patient, the higher the vWF:Ag level, and the longer the FⅧ half-life. Individual administration is required based on the FⅧ PK parameters to optimize prophylaxis treatment.
Authors
- Zhijuan Pan (ORCID: https://orcid.org/0000-0001-9744-0720)
- Ying Zhang (ORCID: https://orcid.org/0000-0003-3139-3524)
- Wenliang Lu
- Jiajia Sun (ORCID: https://orcid.org/0000-0002-6839-4136)
- Xiaohui Guo (ORCID: https://orcid.org/0000-0002-5588-0995)
- Zhi Li (ORCID: https://orcid.org/0000-0003-1927-9294)
- Bo Jiang (ORCID: https://orcid.org/0000-0002-7233-0186)
- Yanru Guo (ORCID: https://orcid.org/0009-0007-6765-8084)
- Zhiping Guo (ORCID: https://orcid.org/0000-0003-0454-1149)
- Jin-Yu Hao
- Zhifang Guo
- Jingjing Wang (ORCID: https://orcid.org/0009-0001-5376-8836)
- Xin Wang (ORCID: https://orcid.org/0000-0003-3630-1676)
Institutions
- Taiyuan Central Hospital (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-10-01
- DOI
- https://doi.org/10.19746/j.cnki.issn.1009-2137.2024.05.032
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article