[Mechanism of Huayu Jiedu Decoction in Inhibiting Malignant Biological Characteristics of Multiple Myeloma].
Huayu Jiedu Decoction can inhibit the proliferative activity of U266 cells and induce programmed death. Its molecular mechanism may be related to regulating the expression of apoptotic proteins, inhibiting the activation of TLR4/NF-κB pathway and down-regulating the expression of <i>HMGB1</i> and <i>IL-6</i> mRNA.
Authors
- Yan-Quan Liu
- Zhimin Yan (ORCID: https://orcid.org/0000-0002-0751-7374)
- Hailiang Li (ORCID: https://orcid.org/0000-0001-6454-0565)
- Zhuoyu Li (ORCID: https://orcid.org/0009-0006-9858-6733)
- Yili Wang (ORCID: https://orcid.org/0000-0002-7649-3740)
- Xiaoyun Chen
- Jie Lin
Institutions
- Guangdong Medical College (CN)
- Dongguan People’s Hospital (CN)
- First Affiliated Hospital of Gannan Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-10-01
- DOI
- https://doi.org/10.19746/j.cnki.issn.1009-2137.2024.05.021
- Citations
- 1
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article