Circulating Autoantibodies in Adults with Hashimoto’s Thyroiditis: New Insights from a Single-Center, Cross-Sectional Study
HT is significantly associated with a higher prevalence of circulating autoantibodies, such as APCA and atypical ANCA, which may indicate a heightened risk for autoimmune gastritis and broader autoimmune involvement. Detecting these autoantibodies in HT patients could serve as markers for more severe autoimmune dysfunction. These findings emphasize the need for proactive screening, especially in older patients and those with elevated A-TPO levels. Further research is essential to better understand the clinical implications and develop targeted management strategies for these patients.
Authors
- Omar Tripolino (ORCID: https://orcid.org/0000-0003-0914-3756)
- Francesco Dragone (ORCID: https://orcid.org/0009-0009-4561-8529)
- Marta Greco (ORCID: https://orcid.org/0000-0003-4192-3891)
- DANIELA PATRIZIA FOTI (ORCID: https://orcid.org/0000-0002-9536-5736)
- Eusebio Chiefari (ORCID: https://orcid.org/0000-0001-5329-3124)
- Antonio Torchia
- Maria Mirabelli (ORCID: https://orcid.org/0000-0002-6427-7186)
- Antonio Brunetti (ORCID: https://orcid.org/0000-0003-1533-8779)
- Roberta Misiti (ORCID: https://orcid.org/0009-0001-5895-7062)
- Denise Casella
Institutions
- Magna Graecia University (IT)
Publication Details
- Journal
- Diagnostics
- Published
- 2024-10-31
- DOI
- https://doi.org/10.3390/diagnostics14212450
- Citations
- 7
- Primary Topic
- Thyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.50