High throughput sequencing reveals alterations in B cell receptor repertoires associated with the progression of hepatic cirrhosis to hepatocellular carcinoma

Our results corroborated that the BCR diversity and composition could be closely correlated with hepatic carcinogenesis. And BCR repertoire may be used to predict the progression of HCC and design targeting immunotherapy in the near future.

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Publication Details

Journal
Tumori Journal
Published
2024-10-31
DOI
https://doi.org/10.1177/03008916241290638
Primary Topic
Hepatitis C virus research
Type
article
Field-Weighted Citation Impact
0.00

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article

High throughput sequencing reveals alterations in B cell receptor repertoires associated with the progression of hepatic cirrhosis to hepatocellular carcinoma

Yingying Zhao, Runze Jiang, Fengyan Wang, Kun Li et al.
Tumori Journal
Hepatitis C virus research
article

High throughput sequencing reveals alterations in B cell receptor repertoires associated with the progression of hepatic cirrhosis to hepatocellular carcinoma

Yingying Zhao, Runze Jiang, Fengyan Wang, Kun Li, Ziqiang Li, Changqing Xu, Xiaofei Lei, Qiwei Cao
article en

Abstract

Our results corroborated that the BCR diversity and composition could be closely correlated with hepatic carcinogenesis. And BCR repertoire may be used to predict the progression of HCC and design targeting immunotherapy in the near future.

Tumori JournalVol. 110(6)
Shandong University of Traditional Chinese Medicine (CN), Shandong Provincial QianFoShan Hospital (CN), Shandong First Medical University (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 68%
Hepatitis C virus research
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