Point-of-care test of blood Plasmodium RNA within a Pasteur pipette using a novel isothermal amplification without nucleic acid purification
Designed to improve the accessibility of molecular detection in resource-limited settings, pp-IPA's simplicity, affordability, high sensitivity/specificity, and minimal equipment requirements make it a promising point-of-care pathogen identification tool in resource-constrained regions.
Authors
- Lihua Fan (ORCID: https://orcid.org/0000-0001-8308-5713)
- Zhi Zheng (ORCID: https://orcid.org/0000-0002-4049-010X)
- Lyu Xie (ORCID: https://orcid.org/0000-0001-9074-4238)
- Xiaodong Sun (ORCID: https://orcid.org/0000-0002-6849-7880)
- Jiyu Xu
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Yunnan Institute of Parasitic Diseases (CN)
Publication Details
- Journal
- Infectious Diseases of Poverty
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1186/s40249-024-01255-8
- Citations
- 1
- Primary Topic
- Biosensors and Analytical Detection
- Type
- article
- Field-Weighted Citation Impact
- 0.18
Funders
- National Major Science and Technology Projects of China