Association between patient medications and postoperative outcomes in early-stage non-small cell lung cancer
The number of medications prescribed preoperatively is associated with short- and long-term postoperative outcomes for early-stage NSCLC, even when adjusting for several covariates including age and comorbidity burden. Patients prescribed a higher number of medications acting primarily on the respiratory and nervous systems are at elevated risk for postoperative adverse events after curative-intent resection. Prescription medications may be a reliable tool to assess comorbidities and perioperative risk for patients with NSCLC.
Authors
- Carley Pickett
- Nikki E. Rossetti (ORCID: https://orcid.org/0000-0001-5218-0902)
- Mayank R. Patel (ORCID: https://orcid.org/0000-0002-0210-9750)
- Su‐Hsin Chang (ORCID: https://orcid.org/0000-0001-5872-9556)
- Ruben G. Nava (ORCID: https://orcid.org/0000-0001-5685-9445)
- Ana A. Baumann (ORCID: https://orcid.org/0000-0002-4523-0147)
- Daniel Kreisel (ORCID: https://orcid.org/0000-0002-7711-8651)
- Martin William Schoen (ORCID: https://orcid.org/0000-0001-6388-5553)
- Benjamin D. Kozower (ORCID: https://orcid.org/0000-0002-9059-5807)
- Brendan T. Heiden (ORCID: https://orcid.org/0000-0002-0116-7377)
- Varun Puri (ORCID: https://orcid.org/0000-0001-7761-8421)
- Deepika Gopukumar (ORCID: https://orcid.org/0000-0003-0820-5986)
- Steven Tohmasi (ORCID: https://orcid.org/0000-0002-0904-6692)
- Bryan F. Meyers (ORCID: https://orcid.org/0000-0003-2720-0312)
- Whitney S. Brandt (ORCID: https://orcid.org/0000-0003-3839-7667)
- Daniel B. Eaton (ORCID: https://orcid.org/0000-0001-9819-2159)
- Yan Yan
- Theodore Thomas
Institutions
- Washington University in St. Louis (US)
- VA St. Louis Health Care System (US)
- Saint Louis University (US)
Publication Details
- Journal
- Journal of Thoracic Disease
- Published
- 2024-10-01
- DOI
- https://doi.org/10.21037/jtd-24-803
- Citations
- 4
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 1.68
Funders
- U.S. Department of Defense
- Society of Thoracic Surgeons
- National Institutes of Health
- National Cancer Institute