The diagnostic value of hydroxyproline combined with tuberculosis infection T lymphocyte spot assay in pulmonary tuberculosis
The expression of HYP in the serum and BALF of patients with PTB was higher than that of control group, and the expression of HYP was correlated with some clinical indicators. HYP demonstrated good sensitivity and specificity for the primary screening of PTB and higher sensitivity and specificity in the diagnosis of HYP when combined with TSPOT.TB. It may thus have certain value for auxiliary diagnosis in clinic.
Authors
- Zhongkun Ding
- Min Yao (ORCID: https://orcid.org/0000-0003-1815-3702)
- Keyun Bian
- Shengyan Qu
- Jingjing Ren (ORCID: https://orcid.org/0000-0002-6427-4364)
- Yougang Zhai (ORCID: https://orcid.org/0009-0001-2032-4163)
- Jinling Chen (ORCID: https://orcid.org/0000-0003-2992-6571)
- Ming Ni (ORCID: https://orcid.org/0000-0001-9465-2787)
- Yao Fan
- Feifan Xu (ORCID: https://orcid.org/0000-0003-0530-0654)
- Bin Liu (ORCID: https://orcid.org/0000-0002-7791-1289)
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
Publication Details
- Journal
- Journal of Thoracic Disease
- Published
- 2024-10-01
- DOI
- https://doi.org/10.21037/jtd-24-1585
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00