In silico identification and verification of Tanshinone IIA-related prognostic genes in hepatocellular carcinoma
Regulating the expression of TanIIA-related gene signatures (ALB, SRC and ESR1), and inhibiting the SRC/MAPK/ERK signaling axis might potentially contribute to the TanIIA treatment of HCC. And the three gene signatures could be identified for predicting the prognosis of HCC, which may provide novel biomarkers for HCC treatment.
Authors
- Shuai Ren (ORCID: https://orcid.org/0000-0003-4902-6298)
- Yinxing Zhu (ORCID: https://orcid.org/0000-0002-7417-9109)
- Tianjiong Luo
- Zhongchi Xu (ORCID: https://orcid.org/0009-0006-9385-1809)
- Zhongai Zhang
- Kun Cheng (ORCID: https://orcid.org/0009-0001-4352-976X)
- Lichao Qian (ORCID: https://orcid.org/0009-0006-3071-3011)
- Xiaolong He (ORCID: https://orcid.org/0000-0002-1509-8739)
- Zhao Gao (ORCID: https://orcid.org/0009-0002-7557-970X)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Nanjing Tech University (CN)
- Taizhou First People's Hospital (CN)
- Jiangsu Province Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-10-31
- DOI
- https://doi.org/10.3389/fimmu.2024.1482914
- Citations
- 7
- Primary Topic
- Traditional Chinese Medicine Analysis
- Type
- article
- Field-Weighted Citation Impact
- 5.01
Funders
- Jiangsu Commission of Health
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Government of Jiangsu Province
- Nanjing University of Chinese Medicine
- Nanjing University
- Jiangsu Association for Science and Technology